Only ET is with Courteney Cox, David Arquette, Emma Roberts and Neve Campbell on the set of Wes Craven‘s highly anticipated sequel SCREAM 4, 10 years after the last box office smash!

“It’s like going back to summer camp,” Neve tells ET. “The first film was such a blast for all us. At the time we had no idea how successful the film would be. … Coming back to it now after years of people enjoying them and seeing each other again, it’s nice.“

“You see some of the old, and some of the new, and something borrowed and something blue,” says Wes of the fourth installment, which reunites Courteney, David and Neve onscreen and also introduces a younger generation of up-and-coming actors.

“A lot of the audience that will see this film were infants when we made the others,” explains Wes. “I think the older actors are well-known, but they’re a little bit at the parental layer of consciousness for a lot of the audience, so it’ll be kind of fun to see where their stories are going, but it’s also great to introduce new characters and see how they’re going to factor in with things.”

“We all reunite at the beginning of the movie,” says Courteney, explaining that her character, Gale Weathers, has given up her job as a reporter to marry Deputy Dewey (played by David) and write books. “She’s written six STAB books and she has writer’s block, and she’s pretty bored, pretty miserable, pretty desperate, and all of a sudden some murders start happening and her life starts to look up. She likes a good murder.”

In addition to its huge success, the SCREAM franchise also carries a lot of weight with Courteney and David because they first met and fell in love on the project.

“I can remember the day I met him like it was yesterday,” says Courteney, who credits Wes as “really instrumental” in bringing them together. “SCREAM 1 was really an intense crush and all that stuff, and SCREAM 2 we didn’t get along so well, and then SCREAM 3 we had just gotten married, and then SCREAM 4 we have [our six-year-old daughter] Coco, so it’s just been an evolution of things that have happened to us.”

“It’s been good having the whole family here,” says David, who reports that Coco is really into “Little House on the Prairie” right now. “That’s been the biggest change I would say.”

“It’s really doubly lovely,” adds Wes, “because I had a little bit to do with them getting together, and they got married, and they’ve had a good marriage and they have a wonderful little child, and it’s great icing on the cake.”

SCREAM 4 is set to scare up some laughs in April of 2011.